Ligand activation induces different conformational changes in CXCR3 receptor isoforms as evidenced by plasmon waveguide resonance (PWR)

The chemokine receptor CXCR3 plays important roles in angiogenesis, inflammation and cancer. Activation studies and biological functions of CXCR3 are complex due to the presence of spliced isoforms. CXCR3-A is known as a pro-tumor receptor whereas CXCR3-B exhibits anti-tumor properties. Here, we foc...

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Detalles Bibliográficos
Autores principales: Boyé, K., Billottet, C., Pujol, N., Alves, I. D., Bikfalvi, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587768/
https://www.ncbi.nlm.nih.gov/pubmed/28878333
http://dx.doi.org/10.1038/s41598-017-11151-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587768/
https://www.ncbi.nlm.nih.gov/pubmed/28878333
http://dx.doi.org/10.1038/s41598-017-11151-x

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