MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation

Super-enhancers (SEs) are cis-regulatory elements enriching lineage specific key transcription factors (TFs) to form hotspots. A paucity of identification and functional dissection promoted us to investigate SEs during myoblast differentiation. ChIP-seq analysis of histone marks leads to the uncover...

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Detalles Bibliográficos
Autores principales: Peng, Xianlu L., So, Karl K., He, Liangqiang, Zhao, Yu, Zhou, Jiajian, Li, Yuying, Yao, Mingze, Xu, Bo, Zhang, Suyang, Yao, Hongjie, Hu, Ping, Sun, Hao, Wang, Huating
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587775/
https://www.ncbi.nlm.nih.gov/pubmed/28575289
http://dx.doi.org/10.1093/nar/gkx488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587775/
https://www.ncbi.nlm.nih.gov/pubmed/28575289
http://dx.doi.org/10.1093/nar/gkx488

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