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Prediction of genome-wide DNA methylation in repetitive elements

DNA methylation in repetitive elements (RE) suppresses their mobility and maintains genomic stability, and decreases in it are frequently observed in tumor and/or surrogate tissues. Averaging methylation across RE in genome is widely used to quantify global methylation. However, methylation may vary...

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Detalles Bibliográficos
Autores principales: Zheng, Yinan, Joyce, Brian T., Liu, Lei, Zhang, Zhou, Kibbe, Warren A., Zhang, Wei, Hou, Lifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587781/
https://www.ncbi.nlm.nih.gov/pubmed/28911103
http://dx.doi.org/10.1093/nar/gkx587