Mediator binds to boundaries of chromosomal interaction domains and to proteins involved in DNA looping, RNA metabolism, chromatin remodeling, and actin assembly

Mediator is a multi-unit molecular complex that plays a key role in transferring signals from transcriptional regulators to RNA polymerase II in eukaryotes. We have combined biochemical purification of the Saccharomyces cerevisiae Mediator from chromatin with chromatin immunoprecipitation in order t...

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Detalles Bibliográficos
Autores principales: Chereji, Răzvan V., Bharatula, Vasudha, Elfving, Nils, Blomberg, Jeanette, Larsson, Miriam, Morozov, Alexandre V., Broach, James R., Björklund, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587782/
https://www.ncbi.nlm.nih.gov/pubmed/28575439
http://dx.doi.org/10.1093/nar/gkx491

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