Unencumbered Pol β lyase activity in nucleosome core particles

Packaging of DNA into the nucleosome core particle (NCP) is considered to exert constraints to all DNA-templated processes, including base excision repair where Pol β catalyzes two key enzymatic steps: 5′-dRP lyase gap trimming and template-directed DNA synthesis. Despite its biological significance...

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Detalles Bibliográficos
Autores principales: Rodriguez, Yesenia, Howard, Michael J., Cuneo, Matthew J., Prasad, Rajendra, Wilson, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587807/
https://www.ncbi.nlm.nih.gov/pubmed/28911106
http://dx.doi.org/10.1093/nar/gkx593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587807/
https://www.ncbi.nlm.nih.gov/pubmed/28911106
http://dx.doi.org/10.1093/nar/gkx593

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