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Unencumbered Pol β lyase activity in nucleosome core particles

Packaging of DNA into the nucleosome core particle (NCP) is considered to exert constraints to all DNA-templated processes, including base excision repair where Pol β catalyzes two key enzymatic steps: 5′-dRP lyase gap trimming and template-directed DNA synthesis. Despite its biological significance...

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Detalles Bibliográficos
Autores principales:	Rodriguez, Yesenia, Howard, Michael J., Cuneo, Matthew J., Prasad, Rajendra, Wilson, Samuel H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587807/ https://www.ncbi.nlm.nih.gov/pubmed/28911106 http://dx.doi.org/10.1093/nar/gkx593

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