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The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe?
We aimed to assess the epidemiology and spatiotemporal patterns of influenza in the World Health Organization (WHO) European Region and evaluate the validity of partitioning the Region into five influenza transmission zones (ITZs) as proposed by the WHO. We used the FluNet database and included over...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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European Centre for Disease Prevention and Control (ECDC)
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587899/ https://www.ncbi.nlm.nih.gov/pubmed/28877844 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.35.30606 |
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author | Caini, Saverio Alonso, Wladimir J Séblain, Clotilde El-Guerche Schellevis, François Paget, John |
author_facet | Caini, Saverio Alonso, Wladimir J Séblain, Clotilde El-Guerche Schellevis, François Paget, John |
author_sort | Caini, Saverio |
collection | PubMed |
description | We aimed to assess the epidemiology and spatiotemporal patterns of influenza in the World Health Organization (WHO) European Region and evaluate the validity of partitioning the Region into five influenza transmission zones (ITZs) as proposed by the WHO. We used the FluNet database and included over 650,000 influenza cases from 2000 to 2015. We analysed the data by country and season (from July to the following June). We calculated the median proportion of cases caused by each virus type in a season, compared the timing of the primary peak between countries and used a range of cluster analysis methods to assess the degree of overlap between the WHO-defined and data-driven ITZs. Influenza A and B caused, respectively, a median of 83% and 17% cases in a season. There was a significant west-to-east and non-significant (p = 0.10) south-to-north gradient in the timing of influenza activity. Typically, influenza peaked in February and March; influenza A earlier than influenza B. Most countries in the WHO European Region would fit into two ITZs: ‘Western Europe’ and ‘Eastern Europe’; countries bordering Asia may be better placed into extra-European ITZs. Our findings have implications for the presentation of surveillance data and prevention and control measures in this large WHO Region. |
format | Online Article Text |
id | pubmed-5587899 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-55878992017-09-15 The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? Caini, Saverio Alonso, Wladimir J Séblain, Clotilde El-Guerche Schellevis, François Paget, John Euro Surveill Research Article We aimed to assess the epidemiology and spatiotemporal patterns of influenza in the World Health Organization (WHO) European Region and evaluate the validity of partitioning the Region into five influenza transmission zones (ITZs) as proposed by the WHO. We used the FluNet database and included over 650,000 influenza cases from 2000 to 2015. We analysed the data by country and season (from July to the following June). We calculated the median proportion of cases caused by each virus type in a season, compared the timing of the primary peak between countries and used a range of cluster analysis methods to assess the degree of overlap between the WHO-defined and data-driven ITZs. Influenza A and B caused, respectively, a median of 83% and 17% cases in a season. There was a significant west-to-east and non-significant (p = 0.10) south-to-north gradient in the timing of influenza activity. Typically, influenza peaked in February and March; influenza A earlier than influenza B. Most countries in the WHO European Region would fit into two ITZs: ‘Western Europe’ and ‘Eastern Europe’; countries bordering Asia may be better placed into extra-European ITZs. Our findings have implications for the presentation of surveillance data and prevention and control measures in this large WHO Region. European Centre for Disease Prevention and Control (ECDC) 2017-08-31 /pmc/articles/PMC5587899/ /pubmed/28877844 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.35.30606 Text en This article is copyright of The Authors, 2017. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Research Article Caini, Saverio Alonso, Wladimir J Séblain, Clotilde El-Guerche Schellevis, François Paget, John The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? |
title | The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? |
title_full | The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? |
title_fullStr | The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? |
title_full_unstemmed | The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? |
title_short | The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? |
title_sort | spatiotemporal characteristics of influenza a and b in the who european region: can one define influenza transmission zones in europe? |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587899/ https://www.ncbi.nlm.nih.gov/pubmed/28877844 http://dx.doi.org/10.2807/1560-7917.ES.2017.22.35.30606 |
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