Broad-Host-Range Expression Reveals Native and Host Regulatory Elements That Influence Heterologous Antibiotic Production in Gram-Negative Bacteria

Heterologous expression has become a powerful tool for studying microbial biosynthetic gene clusters (BGCs). Here, we extend the transformation-associated recombination cloning and heterologous expression platform for microbial BGCs to include Gram-negative proteobacterial expression hosts. Using a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jia Jia, Tang, Xiaoyu, Zhang, Michelle, Nguyen, Darlene, Moore, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587914/
https://www.ncbi.nlm.nih.gov/pubmed/28874475
http://dx.doi.org/10.1128/mBio.01291-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587914/
https://www.ncbi.nlm.nih.gov/pubmed/28874475
http://dx.doi.org/10.1128/mBio.01291-17

Ejemplares similares