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Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer

Metformin is a biguanide employed in treating type II diabetes. Its potential efficacy for treating cancer has been demonstrated epidemiologically (lower cancer incidence in metformin users compared with users of sulfonylureas or insulin) and mechanistically, primarily in cell culture. Metformin dec...

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Detalles Bibliográficos
Autores principales:	Thompson, Matthew D., Lubet, Ronald A., Mccormick, David L., Clapper, Margie L., Bode, Ann M., Juliana, M. Margaret, Moeinpour, Fariba, Grubbs, Clinton J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587978/ https://www.ncbi.nlm.nih.gov/pubmed/28927103 http://dx.doi.org/10.3892/ol.2017.6632

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