Gimeracil enhances the antitumor effect of cisplatin in oral squamous cell carcinoma cells in vitro and in vivo

Gimeracil or 5-chloro-2,4-dihydroxypyridine (CDHP) enhances the antitumor effects of 5-fluorouracil (5-FU) by inhibiting dihydropyrimidine dehydrogenase (DPD), which is involved in the degradation of 5-FU. CDHP, as part of a combination therapy, was also reported to exert a radiosensitizing effect....

Descripción completa

Detalles Bibliográficos
Autores principales: Harada, Koji, Ferdous, Tarannum, Harada, Toyoko, Takenawa, Takanori, Ueyama, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587992/
https://www.ncbi.nlm.nih.gov/pubmed/28927087
http://dx.doi.org/10.3892/ol.2017.6602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587992/
https://www.ncbi.nlm.nih.gov/pubmed/28927087
http://dx.doi.org/10.3892/ol.2017.6602

Ejemplares similares