Interleukin-6 identified as an important factor in hypoxia- and aldehyde dehydrogenase-based gefitinib adaptive resistance in non-small cell lung cancer cells

Gefitinib resistance and relapse of the disease were the greatest challenges facing clinical therapy of non-small-cell lung cancer (NSCLC). Of note, regarding the hypoxia condition in solid tumor tissues in vivo, roles of hypoxia in gefitinib adaptive resistance and its association with lung cancer...

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Detalles Bibliográficos
Autores principales: An, Shi-Min, Lei, Hui-Min, Ding, Xu-Ping, Sun, Fan, Zhang, Chun, Tang, Ya-Bin, Chen, Hong-Zhuan, Shen, Ying, Zhu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588073/
https://www.ncbi.nlm.nih.gov/pubmed/28927099
http://dx.doi.org/10.3892/ol.2017.6613

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