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Highly Improved Electrospray Ionization-Mass Spectrometry Detection of G-Quadruplex-Folded Oligonucleotides and Their Complexes with Small Molecules

[Image: see text] G-quadruplexes are nucleic acids structures stabilized by physiological concentration of potassium ions. Because low stability G-quadruplexes are hardly detectable by mass spectrometry, we optimized solvent conditions: isopropanol in a triethylamine/hexafluoroisopropanol mixture hi...

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Detalles Bibliográficos
Autores principales:	Scalabrin, Matteo, Palumbo, Manlio, Richter, Sara N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588092/ https://www.ncbi.nlm.nih.gov/pubmed/28787153 http://dx.doi.org/10.1021/acs.analchem.7b01282

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