Cargando…

All-trans retinoic acid enhances temozolomide-induced autophagy in human glioma cells U251 via targeting Keap1/Nrf2/ARE signaling pathway

The present study evaluated the retinoic acid (RA) enhancement of temozolomide (TMZ) effects on the human glioma cells U251 and explored its underlying molecular mechanism. The cell growth was detected using the MTT assay and the cell cycle was assessed by flow cytometry. Cell apoptosis was analyzed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Lin, Li, Hongyuan, Zhan, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588105/ https://www.ncbi.nlm.nih.gov/pubmed/28927033 http://dx.doi.org/10.3892/ol.2017.6482

Ejemplares similares

Effect of temozolomide on livin and caspase-3 in U251 glioma stem cells
por: LI, GENHUA, et al.
Publicado: (2015)

Corilagin induces apoptosis and autophagy in NRF2-addicted U251 glioma cell line
por: Liu, Jilan, et al.
Publicado: (2021)

Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL
por: Tang, Jun-Hai, et al.
Publicado: (2017)

Downregulation of ROCK2 through Nanocomplex Sensitizes the Cytotoxic Effect of Temozolomide in U251 Glioma Cells
por: Wen, Xiaojun, et al.
Publicado: (2014)

Data supporting the inability of indomethacin to induce autophagy in U251 glioma cells
por: Pantovic, Aleksandar, et al.
Publicado: (2017)

Correction: Downregulation of ROCK2 through Nanocomplex Sensitizes the Cytotoxic Effect of Temozolomide in U251 Glioma Cells
Publicado: (2014)

RRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells
por: Wallace, Aaron S., et al.
Publicado: (2016)

The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells
por: Li, Jun, et al.
Publicado: (2009)

BmK CT enhances the sensitivity of temozolomide-induced apoptosis of malignant glioma U251 cells in vitro through blocking the AKT signaling pathway
por: Du, Jun, et al.
Publicado: (2018)

Newcastle disease virus triggers autophagy in U251 glioma cells to enhance virus replication
por: Meng, Chunchun, et al.
Publicado: (2012)

All-trans retinoic acid upregulates VEGF expression in glioma cells in vitro
por: Liang, Chen, et al.
Publicado: (2013)

Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells
por: Коbylinska, Lesya I., et al.
Publicado: (2017)

MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy
por: Xu, Jing, et al.
Publicado: (2018)

Suppressing H19 Modulates Tumorigenicity and Stemness in U251 and U87MG Glioma Cells
por: Li, Weiguo, et al.
Publicado: (2016)

All-trans retinoic acid therapy induces asymmetric division of glioma stem cells from the U87MG cell line
por: Wang, Ruizhi, et al.
Publicado: (2019)

Keap1/Nrf2 Signaling Pathway
por: Sykiotis, Gerasimos P.
Publicado: (2021)

Gallic acid‐gold nanoparticles enhance radiation‐induced cell death of human glioma U251 cells
por: Jing, Zhou, et al.
Publicado: (2020)

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
por: Mizunoe, Yuhei, et al.
Publicado: (2017)

Targeting autophagy to sensitive glioma to temozolomide treatment
por: Yan, Yuanliang, et al.
Publicado: (2016)

Synergistic Effects of Taurine and Temozolomide Via Cell Proliferation Inhibition and Apoptotic Induction on U-251 MG Human Glioblastoma Cells
por: Surarak, Thanakorn, et al.
Publicado: (2021)

Identification of U251 glioma stem cells and their heterogeneous stem-like phenotypes
por: ZHANG, SUOJUN, et al.
Publicado: (2013)

Increasing radiosensitivity with the downregulation of cofilin-1 in U251 human glioma cells
por: DU, HUA-QING, et al.
Publicado: (2015)

Effects of syndecan-1 on the expression of syntenin and the migration of U251 glioma cells
por: Chen, Jun, et al.
Publicado: (2017)

Effects of mir-128a on the invasion and proliferation of glioma U251 cells
por: Hu, Guozhang, et al.
Publicado: (2019)

The KEAP1/NRF2 Signaling Pathway in Keratinization
por: Ishitsuka, Yosuke, et al.
Publicado: (2020)

Role and Mechanism of Keap1/Nrf2 Signaling Pathway in the Regulation of Autophagy in Alleviating Pulmonary Fibrosis
por: Dong, Zhaoxing, et al.
Publicado: (2022)

Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cells
por: Du, Zhanhui, et al.
Publicado: (2018)

All-Trans Retinoic Acid Fosters the Multifarious U87MG Cell Line as a Model of Glioblastoma
por: Pokorná, Markéta, et al.
Publicado: (2021)

Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway
por: Zhou, Jiabin, et al.
Publicado: (2019)

Molecular profiling of MPS1 gene silencing in U251 glioma cell line
por: Shankavaram, Uma, et al.
Publicado: (2015)

Pharmacokinetics of All‐trans Retinoic Acid in Pediatric Patients with Leukemia
por: Takitani, Kimitaka, et al.
Publicado: (1995)

Transdifferentiation of Myoblasts Into Adipocytes by All-Trans-Retinoic Acid in Avian
por: Kim, Dong-Hwan, et al.
Publicado: (2022)

Potential Therapeutic Effect of All-Trans Retinoic Acid on Atherosclerosis
por: Deng, Qile, et al.
Publicado: (2022)

Deregulation of All-Trans Retinoic Acid Signaling and Development in Cancer
por: Brown, Geoffrey
Publicado: (2023)

Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia
por: Gianni’, Maurizio, et al.
Publicado: (2022)

IQGAP1-siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines
por: Diao, Bo, et al.
Publicado: (2017)

KEAP1 and done? Targeting the NRF2 pathway with sulforaphane
por: Dinkova-Kostova, Albena T., et al.
Publicado: (2017)

Coumarins as Modulators of the Keap1/Nrf2/ARE Signaling Pathway
por: Hassanein, Emad H. M., et al.
Publicado: (2020)

Molecular Basis of the KEAP1-NRF2 Signaling Pathway
por: Suzuki, Takafumi, et al.
Publicado: (2023)

Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway
por: Kidokoro, Kengo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_82ji6viivlt674k9rbbq6avjsn