Cargando…

Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis

We studied the clinical effects of percutaneous radiofrequency ablation (RFCA) combined with trans-catheter arterial chemoembolization (TACE) in the treatment of breast cancer with liver metastasis. Eighty-eight patients with a diagnosis of breast cancer with liver metastasis for the first time and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Haijun, Liu, Bin, Long, Houlong, Zhang, Fengfeng, Wang, Silei, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588120/
https://www.ncbi.nlm.nih.gov/pubmed/28927032
http://dx.doi.org/10.3892/ol.2017.6483
_version_ 1783262115224616960
author Wang, Haijun
Liu, Bin
Long, Houlong
Zhang, Fengfeng
Wang, Silei
Li, Feng
author_facet Wang, Haijun
Liu, Bin
Long, Houlong
Zhang, Fengfeng
Wang, Silei
Li, Feng
author_sort Wang, Haijun
collection PubMed
description We studied the clinical effects of percutaneous radiofrequency ablation (RFCA) combined with trans-catheter arterial chemoembolization (TACE) in the treatment of breast cancer with liver metastasis. Eighty-eight patients with a diagnosis of breast cancer with liver metastasis for the first time and patients with liver metastasis after radical mastectomy were consecutively selected. The subjects were divided according to the different treatment methods. They were divided either into the control group of 50 cases or the observation group of 38 cases. Breast cancer patients underwent radical mastectomy with conventional systemic venous chemotherapy. The liver metastasis control group used TACE, while the observation group combined RFCA with TACE. The two groups were followed up for a median time of 20 months, and the clinical effects were compared. The effective rate of the observation group was higher than that of the control group; differences were statistically significant (P<0.05). There was no differences in the incidence of complications between the two groups (P>0.05). The progression free survival, median survival time and survival rate of the observation group were increased; differences were statistically significant (P<0.05). Therefore, RFCA combined with TACE in the treatment of breast cancer with liver metastasis is safe and effective.
format Online
Article
Text
id pubmed-5588120
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-55881202017-09-18 Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis Wang, Haijun Liu, Bin Long, Houlong Zhang, Fengfeng Wang, Silei Li, Feng Oncol Lett Articles We studied the clinical effects of percutaneous radiofrequency ablation (RFCA) combined with trans-catheter arterial chemoembolization (TACE) in the treatment of breast cancer with liver metastasis. Eighty-eight patients with a diagnosis of breast cancer with liver metastasis for the first time and patients with liver metastasis after radical mastectomy were consecutively selected. The subjects were divided according to the different treatment methods. They were divided either into the control group of 50 cases or the observation group of 38 cases. Breast cancer patients underwent radical mastectomy with conventional systemic venous chemotherapy. The liver metastasis control group used TACE, while the observation group combined RFCA with TACE. The two groups were followed up for a median time of 20 months, and the clinical effects were compared. The effective rate of the observation group was higher than that of the control group; differences were statistically significant (P<0.05). There was no differences in the incidence of complications between the two groups (P>0.05). The progression free survival, median survival time and survival rate of the observation group were increased; differences were statistically significant (P<0.05). Therefore, RFCA combined with TACE in the treatment of breast cancer with liver metastasis is safe and effective. D.A. Spandidos 2017-09 2017-06-27 /pmc/articles/PMC5588120/ /pubmed/28927032 http://dx.doi.org/10.3892/ol.2017.6483 Text en Copyright: © Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Wang, Haijun
Liu, Bin
Long, Houlong
Zhang, Fengfeng
Wang, Silei
Li, Feng
Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis
title Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis
title_full Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis
title_fullStr Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis
title_full_unstemmed Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis
title_short Clinical study of radiofrequency ablation combined with TACE in the treatment of breast cancer with liver metastasis
title_sort clinical study of radiofrequency ablation combined with tace in the treatment of breast cancer with liver metastasis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588120/
https://www.ncbi.nlm.nih.gov/pubmed/28927032
http://dx.doi.org/10.3892/ol.2017.6483
work_keys_str_mv AT wanghaijun clinicalstudyofradiofrequencyablationcombinedwithtaceinthetreatmentofbreastcancerwithlivermetastasis
AT liubin clinicalstudyofradiofrequencyablationcombinedwithtaceinthetreatmentofbreastcancerwithlivermetastasis
AT longhoulong clinicalstudyofradiofrequencyablationcombinedwithtaceinthetreatmentofbreastcancerwithlivermetastasis
AT zhangfengfeng clinicalstudyofradiofrequencyablationcombinedwithtaceinthetreatmentofbreastcancerwithlivermetastasis
AT wangsilei clinicalstudyofradiofrequencyablationcombinedwithtaceinthetreatmentofbreastcancerwithlivermetastasis
AT lifeng clinicalstudyofradiofrequencyablationcombinedwithtaceinthetreatmentofbreastcancerwithlivermetastasis