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PARK2 negatively regulates the metastasis and epithelial-mesenchymal transition of glioblastoma cells via ZEB1

Glioblastoma multiforme (GBM), one of the most aggressive human malignant brain tumors, is induced by multiple complex pathological mechanisms. The main cause of mortality in patients with GBM is the invasion-metastasis cascade of tumor cells. The dysfunction of Parkinson protein 2 E3 ubiquitin prot...

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Detalles Bibliográficos
Autores principales: Wang, Haiyang, Jiang, Zhenfeng, Na, Meng, Ge, Haitao, Tang, Chongyang, Shen, Hong, Lin, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588166/
https://www.ncbi.nlm.nih.gov/pubmed/28928831
http://dx.doi.org/10.3892/ol.2017.6488