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Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction
OBJECTIVE: In this study, we aimed to investigate the left atrial (LA) electrical and mechanical functions in patients with metabolic syndrome (MetS). SUBJECTS AND METHODS: The study population consisted of 87 patients with MetS and 67 controls. Intra-atrial and interatrial electromechanical delays...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588191/ https://www.ncbi.nlm.nih.gov/pubmed/25592764 http://dx.doi.org/10.1159/000368754 |
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author | Yilmaz, Hale Özcan, Kazım Serhan Sayar, Nurten Kemaloglu, Tugba Gungor, Baris Erer, Betul Yilmaz, Mehmet Gurkan, Ufuk Cakmak, Nazmiye Oz, Dilaver Calik, Ali Nazmi Bolca, Osman |
author_facet | Yilmaz, Hale Özcan, Kazım Serhan Sayar, Nurten Kemaloglu, Tugba Gungor, Baris Erer, Betul Yilmaz, Mehmet Gurkan, Ufuk Cakmak, Nazmiye Oz, Dilaver Calik, Ali Nazmi Bolca, Osman |
author_sort | Yilmaz, Hale |
collection | PubMed |
description | OBJECTIVE: In this study, we aimed to investigate the left atrial (LA) electrical and mechanical functions in patients with metabolic syndrome (MetS). SUBJECTS AND METHODS: The study population consisted of 87 patients with MetS and 67 controls. Intra-atrial and interatrial electromechanical delays (EDs) were measured with tissue Doppler imaging. P-wave dispersion (Pd) was calculated from the 12-lead electrocardiograms. LA volumes were measured echocardiographically by the biplane area-length method. RESULTS: Intra-atrial and interatrial EDs and Pd were significantly higher in patients with MetS (10.3 ± 6.3, 21.0 ± 11.5 and 41.7 ± 10.8) than in controls (7.4 ± 5.5, 12.3 ± 10.4 and 29.2 ± 7.4; p = 0.003, p < 0.001 and p < 0.001, respectively). The LA preatrial contraction volume and active emptying volumes were higher in this population, but the LA passive emptying fraction was lower. In the multivariate linear regression analysis, the presence of MetS, LA active emptying volume and left ventricular early diastolic (E) wave velocity/late diastolic (A) wave velocity (E/A) ratios were independent correlates of interatrial ED (p = 0.002, p = 0.001 and p = 0.025, respectively). CONCLUSIONS: This study showed that intra-atrial and interatrial EDs and Pd were prolonged and LA mechanical functions were impaired in patients with MetS. |
format | Online Article Text |
id | pubmed-5588191 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-55881912017-11-01 Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction Yilmaz, Hale Özcan, Kazım Serhan Sayar, Nurten Kemaloglu, Tugba Gungor, Baris Erer, Betul Yilmaz, Mehmet Gurkan, Ufuk Cakmak, Nazmiye Oz, Dilaver Calik, Ali Nazmi Bolca, Osman Med Princ Pract Original Paper OBJECTIVE: In this study, we aimed to investigate the left atrial (LA) electrical and mechanical functions in patients with metabolic syndrome (MetS). SUBJECTS AND METHODS: The study population consisted of 87 patients with MetS and 67 controls. Intra-atrial and interatrial electromechanical delays (EDs) were measured with tissue Doppler imaging. P-wave dispersion (Pd) was calculated from the 12-lead electrocardiograms. LA volumes were measured echocardiographically by the biplane area-length method. RESULTS: Intra-atrial and interatrial EDs and Pd were significantly higher in patients with MetS (10.3 ± 6.3, 21.0 ± 11.5 and 41.7 ± 10.8) than in controls (7.4 ± 5.5, 12.3 ± 10.4 and 29.2 ± 7.4; p = 0.003, p < 0.001 and p < 0.001, respectively). The LA preatrial contraction volume and active emptying volumes were higher in this population, but the LA passive emptying fraction was lower. In the multivariate linear regression analysis, the presence of MetS, LA active emptying volume and left ventricular early diastolic (E) wave velocity/late diastolic (A) wave velocity (E/A) ratios were independent correlates of interatrial ED (p = 0.002, p = 0.001 and p = 0.025, respectively). CONCLUSIONS: This study showed that intra-atrial and interatrial EDs and Pd were prolonged and LA mechanical functions were impaired in patients with MetS. S. Karger AG 2015-02 2015-01-10 /pmc/articles/PMC5588191/ /pubmed/25592764 http://dx.doi.org/10.1159/000368754 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only. |
spellingShingle | Original Paper Yilmaz, Hale Özcan, Kazım Serhan Sayar, Nurten Kemaloglu, Tugba Gungor, Baris Erer, Betul Yilmaz, Mehmet Gurkan, Ufuk Cakmak, Nazmiye Oz, Dilaver Calik, Ali Nazmi Bolca, Osman Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction |
title | Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction |
title_full | Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction |
title_fullStr | Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction |
title_full_unstemmed | Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction |
title_short | Metabolic Syndrome Is Associated with Atrial Electrical and Mechanical Dysfunction |
title_sort | metabolic syndrome is associated with atrial electrical and mechanical dysfunction |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588191/ https://www.ncbi.nlm.nih.gov/pubmed/25592764 http://dx.doi.org/10.1159/000368754 |
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