Cargando…

Association Study of the TREM2 Gene and Identification of a Novel Variant in Exon 2 in Iranian Patients with Late-Onset Alzheimer's Disease

OBJECTIVE: To analyze the association between TREM2 exon 2 variants and late-onset (sporadic) Alzheimer's disease (AD) in an elderly Iranian population. MATERIALS AND METHODS: Exon 2 of TREM2 in a total of 131 AD patients and 157 controls was genotyped using polymerase chain reaction and Sanger...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mehrjoo, Zohreh, Najmabadi, Amin, Abedini, Seyedeh Sedigheh, Mohseni, Marzieh, Kamali, Koorosh, Najmabadi, Hossein, Khorram Khorshid, Hamid Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2015
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588241/ https://www.ncbi.nlm.nih.gov/pubmed/26021840 http://dx.doi.org/10.1159/000430842

Ejemplares similares

Detection of a rare AXIN2 variant in an Iranian family with hypodontia and oligodontia
por: Safari, Shiva, et al.
Publicado: (2022)

Screening PAX9, MSX1 and WNT10A Mutations in 4 Iranian Families with Non-Syndromic Tooth Agenesis
por: Safari, Shiva, et al.
Publicado: (2020)

Association of MMP2 and MMP9 gene polymorphisms with nonsyndromic cleft lip/palate in an Iranian population
por: Zahedipour, Fatemeh, et al.
Publicado: (2023)

Lack of Association between Tumor Necrosis Factor-alpha -308 G/A Polymorphism and Risk of Developing Late-Onset Alzheimer's Disease in an Iranian Population
por: Manoochehri, Mehdi, et al.
Publicado: (2009)

Association of CALHM1 Gene Polymorphism with Late Onset Alzheimer's Disease in Iranian Population
por: Aqdam, Meysam Jafari, et al.
Publicado: (2010)

Interaction Effect of RsaI and BamHI Polymorphisms of TGFα, BMP2 and BMP4 on the Occurrence of Non-Syndromic Cleft Lip and Palate in Iranian Patients
por: Samadi, Saba, et al.
Publicado: (2018)

Association study of Glutathione S-Transferase polymorphisms and risk of endometriosis in an Iranian population
por: Hassani, Mina, et al.
Publicado: (2016)

Novel CFTR Mutations in Two Iranian Families with Severe Cystic Fibrosis
por: Mohseni, Marzieh, et al.
Publicado: (2016)

A Novel Deletion Mutation in ASPM Gene in an Iranian Family with Autosomal Recessive Primary Microcephaly
por: AKBARIAZAR, Elinaz, et al.
Publicado: (2013)

Evaluation of chromosomal aberrations caused by air pollutants in some taxi drivers from two polluted districts of urban Tehran and its comparison with drivers from rural areas of Lahijan: a pilot study
por: Taghizadeh, Sara, et al.
Publicado: (2014)

Parental cigarette smoking, transforming growth factor-alpha gene variant and the risk of orofacial cleft in Iranian infants
por: Ebadifar, Asghar, et al.
Publicado: (2016)

Whole genome sequencing identifies a duplicated region encompassing Xq13.2q13.3 in a large Iranian family with intellectual disability
por: Mehvari, Sepideh, et al.
Publicado: (2020)

Ccr2-64i and Ccr5 Δ32 Polymorphisms in Patients with Late-Onset Alzheimer’s disease; A Study from Iran (Ccr2-64i And Ccr5 Δ32 Polymorphisms in Alzheimer’s disease)
por: Khorram Khorshid, Hamid Reza, et al.
Publicado: (2012)

Association of the WNT3 Variations and the Risk of Non-Syndromic Cleft Lip and Palate in a Population of Iranian Infants
por: Farrokhi Karibozorg, Homa, et al.
Publicado: (2018)

Identification of a homozygous frameshift mutation in the FGF3 gene in a consanguineous Iranian family: First report of labyrinthine aplasia, microtia, and microdontia syndrome in Iran and literature review
por: Jamshidi, Fereshteh, et al.
Publicado: (2023)

Vitamin D Receptor (VDR) Polymorphisms and Late-Onset Alzheimer’s Disease: An Association Study
por: Khorram Khorshid, Hamid Reza, et al.
Publicado: (2013)

The study of association between reduced folate carrier 1 (RFC1) polymorphism and non-syndromic cleft lip/palate in Iranian population
por: Soghani, Behnoosh, et al.
Publicado: (2017)

Maternal Supplementary Folate Intake, Methylenetetrahydrofolate Reductase (MTHFR) C677T and A1298C Polymorphisms and the Risk of Orofacial Cleft in Iranian Children
por: Ebadifar, Asghar, et al.
Publicado: (2015)

Identifying the causes of recurrent pregnancy loss in consanguineous couples using whole exome sequencing on the products of miscarriage with no chromosomal abnormalities
por: Najafi, Kimia, et al.
Publicado: (2021)

Mutation Analysis of SLC20A2 and SPP2 as Candidate Genes for Familial Idiopathic Basal Ganglia Calcification
por: Ashtari, Fereshteh, et al.
Publicado: (2013)

Arylamine N-acetyltransferase 2 Polymorphisms and the Risk of Endometriosis
por: Fayez, Diman, et al.
Publicado: (2018)

Effects of Herbal Compound (IMOD) on Behavior and Expression of Alzheimer's Disease Related Genes in Streptozotocin-Rat Model of Sporadic Alzheimer’s Disease
por: Bazazzadegan, Niloofar, et al.
Publicado: (2017)

The Effects of Melilotus officinalis Extract on Expression of Daxx, Nfkb and Vegf Genes in the Streptozotocin-Induced Rat Model of Sporadic Alzheimer’s Disease
por: Bazazzadegan, Niloofar, et al.
Publicado: (2017)

Association of Transforming Growth Factor Alpha Polymorphisms with Nonsyndromic Cleft Lip and Palate in Iranian Population
por: Ebadifar, Asghar, et al.
Publicado: (2015)

Exercise prescription for Iranian midlife women
por: Najmabadi, Khadigeh Mirzaii
Publicado: (2010)

Ambivalence Towards Childbirth in a Medicalized Context: A Qualitative Inquiry Among Iranian Mothers
por: Sedigh Mobarakabadi, Sedigheh, et al.
Publicado: (2015)

Iranian hereditary hemochromatosis patients: Baseline characteristics, laboratory data and gene mutations
por: Zamani, Farhad, et al.
Publicado: (2012)

Neuroprotective Effects of Herbal Extract (Rosa canina, Tanacetum vulgare and Urtica dioica) on Rat Model of Sporadic Alzheimer’s Disease
por: Daneshmand, Parvaneh, et al.
Publicado: (2016)

Effects of Ectoine on Behavior and Candidate Genes Expression in ICV-STZ Rat Model of Sporadic Alzheimer’s Disease
por: Bazazzadegan, Niloofar, et al.
Publicado: (2017)

Discrepancy in the results of Y chromosome microdeletions in an Iranian population
por: Saliminejad, Kioomars, et al.
Publicado: (2011)

Distinct genetic variation and heterogeneity of the Iranian population
por: Mehrjoo, Zohreh, et al.
Publicado: (2019)

Evaluating the role of maternal folic acid supplementation in modifying the effects of methylenetetrahydrofolate reductase (C677T and A1298C) gene polymorphisms in oral cleft children
por: Ebadifar, Asghar, et al.
Publicado: (2016)

Methodological errors in screening of Yq microdeletion in Iranian azoospermic men
por: Saliminejad, Kioomars, et al.
Publicado: (2012)

Prevalence of ACTN3 (the athlete gene) R577X polymorphism in Iranian population
por: Fattahi, Z, et al.
Publicado: (2012)

Chromosome abnormality rate among Iranian patients with idiopathic mental retardation from consanguineous marriages
por: Behjati, Farkhondeh, et al.
Publicado: (2011)

An Association Study on IL16 Gene Polymorphisms with the Risk of Sporadic Alzheimer's Disease
por: Khoshbakht, Tayyebeh, et al.
Publicado: (2015)

Attitudes about Sex Selection and Sex Preference in Iranian Couples Referred for Sex Selection Technology
por: Ahmadi, Seyedeh Fatemeh, et al.
Publicado: (2015)

Clinical and Genetic Characteristics of Splicing Variant in CYP27A1 in an Iranian Family with Cerebrotendinous xanthomatosis
por: Rashvand, Zahra, et al.
Publicado: (2021)

The Effect of Xmn -1 Polymorphism and Coinheritance of Alpha Mutations on Age at First Blood Transfusion in Iranian Patients with Homozygote IVSI-5 Mutation
por: Hashemieh, Mozhgan, et al.
Publicado: (2022)

Association of Vascular Endothelial Growth Factor (VEGF) +405 G>C Polymorphism with Endometriosis in an Iranian Population
por: Memariani, Toktam, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_fje4jinhin9fimqn9vov87o6da