Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report

OBJECTIVE: To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation. CLINICAL PRESENTATION AND INTERVENTION: A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in pe...

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Detalles Bibliográficos
Autores principales: Park, Joonhong, Jekarl, Dong Wook, Park, Suk Young, Shin, Soyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588301/
https://www.ncbi.nlm.nih.gov/pubmed/27595536
http://dx.doi.org/10.1159/000450579
Descripción
Sumario:OBJECTIVE: To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation. CLINICAL PRESENTATION AND INTERVENTION: A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in peripheral blood smear. The ABO and Rh blood type before the diagnosis of MM was A+, but the following ABO grouping was interpreted as AB+. The ABO genotype revealed the subtypes A102 and O101, which confirmed her ABO phenotype as A+. CONCLUSION: This was a case of combined group I and III ABO discrepancies mimicking blood group AB.

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