Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report

OBJECTIVE: To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation. CLINICAL PRESENTATION AND INTERVENTION: A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in pe...

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Autores principales: Park, Joonhong, Jekarl, Dong Wook, Park, Suk Young, Shin, Soyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588301/
https://www.ncbi.nlm.nih.gov/pubmed/27595536
http://dx.doi.org/10.1159/000450579
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author Park, Joonhong
Jekarl, Dong Wook
Park, Suk Young
Shin, Soyoung
author_facet Park, Joonhong
Jekarl, Dong Wook
Park, Suk Young
Shin, Soyoung
author_sort Park, Joonhong
collection PubMed
description OBJECTIVE: To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation. CLINICAL PRESENTATION AND INTERVENTION: A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in peripheral blood smear. The ABO and Rh blood type before the diagnosis of MM was A+, but the following ABO grouping was interpreted as AB+. The ABO genotype revealed the subtypes A102 and O101, which confirmed her ABO phenotype as A+. CONCLUSION: This was a case of combined group I and III ABO discrepancies mimicking blood group AB.
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spelling pubmed-55883012017-11-01 Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report Park, Joonhong Jekarl, Dong Wook Park, Suk Young Shin, Soyoung Med Princ Pract Case Report OBJECTIVE: To report a case with unusual ABO discrepancies caused by coexistence of the loss of anti-B isoagglutinin and rouleau formation. CLINICAL PRESENTATION AND INTERVENTION: A 79-year-old female diagnosed as having multiple myeloma (MM) with monoclonal IgG-λ type showed rouleau formation in peripheral blood smear. The ABO and Rh blood type before the diagnosis of MM was A+, but the following ABO grouping was interpreted as AB+. The ABO genotype revealed the subtypes A102 and O101, which confirmed her ABO phenotype as A+. CONCLUSION: This was a case of combined group I and III ABO discrepancies mimicking blood group AB. S. Karger AG 2017-01 2016-09-05 /pmc/articles/PMC5588301/ /pubmed/27595536 http://dx.doi.org/10.1159/000450579 Text en Copyright © 2016 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
spellingShingle Case Report
Park, Joonhong
Jekarl, Dong Wook
Park, Suk Young
Shin, Soyoung
Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report
title Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report
title_full Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report
title_fullStr Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report
title_full_unstemmed Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report
title_short Combined Group I and III ABO Discrepancies in Multiple Myeloma with IgG-Lambda Type: A Case Report
title_sort combined group i and iii abo discrepancies in multiple myeloma with igg-lambda type: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588301/
https://www.ncbi.nlm.nih.gov/pubmed/27595536
http://dx.doi.org/10.1159/000450579
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