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Insulin Prevents Hyperfiltration and Proteinuria but Not Glomerular Hypertrophy and Increases Mesangial Matrix Expansion in Diabetic Rats
OBJECTIVE: The aim of this work was to study the effect of 7 days of strict glycemic control with insulin on glomerular function and structure in streptozotocin (STZ)-diabetic rats. MATERIALS AND METHODS: Three groups of adult male Fischer rats were studied: controls (n = 15), diabetics (n = 15), an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
S. Karger AG
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588318/ https://www.ncbi.nlm.nih.gov/pubmed/27643698 http://dx.doi.org/10.1159/000450864 |