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Molecular Pathogenesis and Clinical Significance of Driver Mutations in Primary Myelofibrosis: A Review

Primary myelofibrosis (PMF) is a rare chronic BCR-ABL1-negative myeloproliferative neoplasm characterized by progressive bone marrow fibrosis, inefficient hematopoiesis, and shortened survival. The clinical manifestations of PMF include splenomegaly, consequent to extramedullary hematopoiesis, pancy...

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Detalles Bibliográficos
Autores principales:	Alshemmari, Salem H., Rajan, Reshmi, Emadi, Ashkan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588514/ https://www.ncbi.nlm.nih.gov/pubmed/27756071 http://dx.doi.org/10.1159/000450956

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