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Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate...

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Autores principales: Kamouka, Somaia, Moran, Wesley J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588552/
https://www.ncbi.nlm.nih.gov/pubmed/28904626
http://dx.doi.org/10.3762/bjoc.13.177
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author Kamouka, Somaia
Moran, Wesley J
author_facet Kamouka, Somaia
Moran, Wesley J
author_sort Kamouka, Somaia
collection PubMed
description Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.
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spelling pubmed-55885522017-09-13 Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines Kamouka, Somaia Moran, Wesley J Beilstein J Org Chem Full Research Paper Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes. Beilstein-Institut 2017-08-31 /pmc/articles/PMC5588552/ /pubmed/28904626 http://dx.doi.org/10.3762/bjoc.13.177 Text en Copyright © 2017, Kamouka and Moran https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Kamouka, Somaia
Moran, Wesley J
Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines
title Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines
title_full Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines
title_fullStr Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines
title_full_unstemmed Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines
title_short Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines
title_sort iodoarene-catalyzed cyclizations of n-propargylamides and β-amidoketones: synthesis of 2-oxazolines
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588552/
https://www.ncbi.nlm.nih.gov/pubmed/28904626
http://dx.doi.org/10.3762/bjoc.13.177
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