Cargando…

Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”

Teratomas are one of the most common tumors in newborn with excellent prognosis arises from totipotent primordial germ cells harboring two or three germ cell layers. The tumor has been titled “Great masquerade.” The teratomas of sacrococcygeal region present with lower limb weakness, urinary or bowe...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Suyash, Sardhara, Jayesh, Sharma, Pradeep, Srivastava, Arun Kumar, Das, Kuntal Kanti, Bhaisora, Kamlesh S., Mehrotra, Anant, Jaiswal, Awadhesh Kumar, Behari, Sanjay, Kumar, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588652/
https://www.ncbi.nlm.nih.gov/pubmed/28904585
http://dx.doi.org/10.4103/jpn.JPN_188_16
_version_ 1783262217512157184
author Singh, Suyash
Sardhara, Jayesh
Sharma, Pradeep
Srivastava, Arun Kumar
Das, Kuntal Kanti
Bhaisora, Kamlesh S.
Mehrotra, Anant
Jaiswal, Awadhesh Kumar
Behari, Sanjay
Kumar, Raj
author_facet Singh, Suyash
Sardhara, Jayesh
Sharma, Pradeep
Srivastava, Arun Kumar
Das, Kuntal Kanti
Bhaisora, Kamlesh S.
Mehrotra, Anant
Jaiswal, Awadhesh Kumar
Behari, Sanjay
Kumar, Raj
author_sort Singh, Suyash
collection PubMed
description Teratomas are one of the most common tumors in newborn with excellent prognosis arises from totipotent primordial germ cells harboring two or three germ cell layers. The tumor has been titled “Great masquerade.” The teratomas of sacrococcygeal region present with lower limb weakness, urinary or bowel obstruction, and swelling at lower back or intrauterine mass in ultrasound or complicated delivery. A 2-month-old male child presented with complaints of swelling over lumbosacral region with discharging punctum since birth. Sagittal T2-weighted magnetic resonance imaging (MRI) of the spine showed myelocele at L5 level forming placode with central defect at L4-S1 and low-lying tethered cord up to L4–L5. The patient was operated, and histopathology surprisingly came to be mature teratoma. We followed the patient with serum beta human chorionic gonadotropin and alpha-fetoprotein markers and MRI. Literature supports complete surgical removal, including coccyx and tumor base. Mature teratoma is considered as benign disease thus even subtotal excision is appropriate but with aggressive follow-up. The difference in recurrence following total compared to subtotal resection is considered insignificant. In this article, we have discussed the management of teratoma in detail. Teratoma with meningomyelocele is a rare entity. There is still dilemma in managing cases and prognosticating parents in such patients. The provisional diagnosis of teratoma should also be considered when child presents as midline sacrococcygeal mass.
format Online
Article
Text
id pubmed-5588652
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-55886522017-09-13 Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise” Singh, Suyash Sardhara, Jayesh Sharma, Pradeep Srivastava, Arun Kumar Das, Kuntal Kanti Bhaisora, Kamlesh S. Mehrotra, Anant Jaiswal, Awadhesh Kumar Behari, Sanjay Kumar, Raj J Pediatr Neurosci Case Report Teratomas are one of the most common tumors in newborn with excellent prognosis arises from totipotent primordial germ cells harboring two or three germ cell layers. The tumor has been titled “Great masquerade.” The teratomas of sacrococcygeal region present with lower limb weakness, urinary or bowel obstruction, and swelling at lower back or intrauterine mass in ultrasound or complicated delivery. A 2-month-old male child presented with complaints of swelling over lumbosacral region with discharging punctum since birth. Sagittal T2-weighted magnetic resonance imaging (MRI) of the spine showed myelocele at L5 level forming placode with central defect at L4-S1 and low-lying tethered cord up to L4–L5. The patient was operated, and histopathology surprisingly came to be mature teratoma. We followed the patient with serum beta human chorionic gonadotropin and alpha-fetoprotein markers and MRI. Literature supports complete surgical removal, including coccyx and tumor base. Mature teratoma is considered as benign disease thus even subtotal excision is appropriate but with aggressive follow-up. The difference in recurrence following total compared to subtotal resection is considered insignificant. In this article, we have discussed the management of teratoma in detail. Teratoma with meningomyelocele is a rare entity. There is still dilemma in managing cases and prognosticating parents in such patients. The provisional diagnosis of teratoma should also be considered when child presents as midline sacrococcygeal mass. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5588652/ /pubmed/28904585 http://dx.doi.org/10.4103/jpn.JPN_188_16 Text en Copyright: © 2017 Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Singh, Suyash
Sardhara, Jayesh
Sharma, Pradeep
Srivastava, Arun Kumar
Das, Kuntal Kanti
Bhaisora, Kamlesh S.
Mehrotra, Anant
Jaiswal, Awadhesh Kumar
Behari, Sanjay
Kumar, Raj
Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”
title Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”
title_full Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”
title_fullStr Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”
title_full_unstemmed Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”
title_short Is it the Monster “Teratoma” or Simply Meningomyelocele: Our Experience of “Histological Surprise”
title_sort is it the monster “teratoma” or simply meningomyelocele: our experience of “histological surprise”
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588652/
https://www.ncbi.nlm.nih.gov/pubmed/28904585
http://dx.doi.org/10.4103/jpn.JPN_188_16
work_keys_str_mv AT singhsuyash isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT sardharajayesh isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT sharmapradeep isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT srivastavaarunkumar isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT daskuntalkanti isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT bhaisorakamleshs isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT mehrotraanant isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT jaiswalawadheshkumar isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT beharisanjay isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise
AT kumarraj isitthemonsterteratomaorsimplymeningomyeloceleourexperienceofhistologicalsurprise