A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome

BACKGROUND: Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme 2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). We postulated that repleting ACE2 using GSK2586881, a recombinant form of human angiotensin-converting enzyme 2 (rhA...

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Detalles Bibliográficos
Autores principales: Khan, Akram, Benthin, Cody, Zeno, Brian, Albertson, Timothy E., Boyd, John, Christie, Jason D., Hall, Richard, Poirier, Germain, Ronco, Juan J., Tidswell, Mark, Hardes, Kelly, Powley, William M., Wright, Tracey J., Siederer, Sarah K., Fairman, David A., Lipson, David A., Bayliffe, Andrew I., Lazaar, Aili L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588692/
https://www.ncbi.nlm.nih.gov/pubmed/28877748
http://dx.doi.org/10.1186/s13054-017-1823-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588692/
https://www.ncbi.nlm.nih.gov/pubmed/28877748
http://dx.doi.org/10.1186/s13054-017-1823-x

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