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Statistical classifiers for diagnosing disease from immune repertoires: a case study using multiple sclerosis

BACKGROUND: Deep sequencing of lymphocyte receptor repertoires has made it possible to comprehensively profile the clonal composition of lymphocyte populations. This opens the door for novel approaches to diagnose and prognosticate diseases with a driving immune component by identifying repertoire s...

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Detalles Bibliográficos
Autores principales: Ostmeyer, Jared, Christley, Scott, Rounds, William H., Toby, Inimary, Greenberg, Benjamin M., Monson, Nancy L., Cowell, Lindsay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588725/
https://www.ncbi.nlm.nih.gov/pubmed/28882107
http://dx.doi.org/10.1186/s12859-017-1814-6