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Minimum infusion rate and adrenocortical function after continuous infusion of the novel etomidate analog ET-26-HCl in rats

BACKGROUND: Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate hydrochloride (ET-26-HCl) shows little suppre...

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Detalles Bibliográficos
Autores principales: Jiang, Junli, Wang, Bin, Zhu, Zhaoqiong, Yang, Jun, Liu, Jin, Zhang, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588785/
https://www.ncbi.nlm.nih.gov/pubmed/28890850
http://dx.doi.org/10.7717/peerj.3693