Threshold effect of G9a/Glp on peripheral nerve injury-induced hypersensitivity

BACKGROUND: Previous studies disclosed the pivotal role of methyltransferase complex G9a/Glp in the pathogenesis of neuropathic hypersensitivity induced by peripheral nerve injury. We observed that higher dose of G9a inhibitor improved nociceptive behavior, but the lower dose worsened pain. The aim...

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Detalles Bibliográficos
Autores principales: Wang, Xian, Shen, Xiaofeng, Ma, Shaolei, Liu, Yusheng, Xu, Shiqin, Wu, Shizheng, Wang, Fuzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588794/
https://www.ncbi.nlm.nih.gov/pubmed/28814147
http://dx.doi.org/10.1177/1744806917729305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588794/
https://www.ncbi.nlm.nih.gov/pubmed/28814147
http://dx.doi.org/10.1177/1744806917729305

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