Cargando…

Threshold effect of G9a/Glp on peripheral nerve injury-induced hypersensitivity

BACKGROUND: Previous studies disclosed the pivotal role of methyltransferase complex G9a/Glp in the pathogenesis of neuropathic hypersensitivity induced by peripheral nerve injury. We observed that higher dose of G9a inhibitor improved nociceptive behavior, but the lower dose worsened pain. The aim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xian, Shen, Xiaofeng, Ma, Shaolei, Liu, Yusheng, Xu, Shiqin, Wu, Shizheng, Wang, Fuzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588794/ https://www.ncbi.nlm.nih.gov/pubmed/28814147 http://dx.doi.org/10.1177/1744806917729305

Ejemplares similares

Dopaminergic inhibition by G9a/Glp complex on tyrosine hydroxylase in nerve injury-induced hypersensitivity
por: Wang, Nan, et al.
Publicado: (2016)

Macrophage migration inhibitory factor mediates peripheral nerve injury-induced hypersensitivity by curbing dopaminergic descending inhibition
por: Wang, Xian, et al.
Publicado: (2018)

The etiological changes of acetylation in peripheral nerve injury–induced neuropathic hypersensitivity
por: Wang, Xian, et al.
Publicado: (2018)

Evodiamine reduced peripheral hypersensitivity on the mouse with nerve injury or inflammation
por: Zhang, Wen-Dong, et al.
Publicado: (2020)

Comparison Between the Use of Ropivacaine Alone and Ropivacaine With Sufentanil in Epidural Labor Analgesia
por: Wang, Xian, et al.
Publicado: (2015)

RNA-Sequencing and Bioinformatics Analysis of Long Noncoding RNAs and mRNAs in the Prefrontal Cortex of Mice Following Repeated Social Defeat Stress
por: Wang, Xian, et al.
Publicado: (2019)

Unmyelinated Low Threshold Mechanoreceptors are Required for Injury-induced Mechanical Hypersensitivity
por: Seal, Rebecca P., et al.
Publicado: (2009)

BDNF produced by cerebral microglia promotes cortical plasticity and pain hypersensitivity after peripheral nerve injury
por: Huang, Lianyan, et al.
Publicado: (2021)

Postoperative Cognitive Dysfunction: Current Developments in Mechanism and Prevention
por: Wang, Wei, et al.
Publicado: (2014)

Modeled Behavior of Neuropathic Pain with Social Defect in Rats: A Preliminary Methodology Evaluation
por: Wang, Xian, et al.
Publicado: (2014)

SPOP mutation induces DNA methylation via stabilizing GLP/G9a
por: Zhang, Jianong, et al.
Publicado: (2021)

Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1
por: Berger, Julie V, et al.
Publicado: (2011)

Selective RNAi-silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury
por: Itson-Zoske, Brandon, et al.
Publicado: (2023)

Treating peripheral nerve injury-induced spinal cord degeneration and neuropathic pain with peripherally administrated stem cells
por: Wang, Zihui, et al.
Publicado: (2022)

Identification of sensory and motor nerve fascicles by immunofluorescence staining after peripheral nerve injury
por: Zhou, Xijie, et al.
Publicado: (2021)

Active immunization with myelin-derived altered peptide ligand reduces mechanical pain hypersensitivity following peripheral nerve injury
por: Perera, Chamini J, et al.
Publicado: (2015)

Anoctamin 1 contributes to inflammatory and nerve-injury induced hypersensitivity
por: Lee, Byeongjun, et al.
Publicado: (2014)

Exosomes-loaded electroconductive nerve dressing for nerve regeneration and pain relief against diabetic peripheral nerve injury
por: Yang, Qinfeng, et al.
Publicado: (2023)

The etiological contribution of GABAergic plasticity to the pathogenesis of neuropathic pain
por: Li, Caijuan, et al.
Publicado: (2019)

A simple model of radial nerve injury in the rhesus monkey to evaluate peripheral nerve repair
por: Wang, Dong, et al.
Publicado: (2014)

Injuries to Peripheral Nerves
por: Connor, F. Powell
Publicado: (1916)

Peripheral Nerve Injuries
por: Slessor, A. J.
Publicado: (1952)

Peripheral Nerve Injuries
por: Seddon, H. J.
Publicado: (1943)

Peripheral NMDA Receptors Mediate Antidromic Nerve Stimulation-Induced Tactile Hypersensitivity in the Rat
por: Jang, Jun Ho, et al.
Publicado: (2015)

G9a/GLP-sensitivity of H3K9me2 Demarcates Two Types of Genomic Compartments
por: Yan, Zixiang, et al.
Publicado: (2020)

MicroRNA-9 regulates mammalian axon regeneration in peripheral nerve injury
por: Jiang, Jingjing, et al.
Publicado: (2017)

The emergence of adolescent onset pain hypersensitivity following neonatal nerve injury
por: Vega-Avelaira, David, et al.
Publicado: (2012)

Dopaminergic Modulation of Orofacial Mechanical Hypersensitivity Induced by Infraorbital Nerve Injury
por: Maegawa, Hiroharu, et al.
Publicado: (2020)

Craniocerebral injury promotes the repair of peripheral nerve injury
por: Wang, Wei, et al.
Publicado: (2014)

Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death
por: Yu, H, et al.
Publicado: (2013)

Peripheral nerve injuries : principles of diagnosis
por: Haymaker, Webb, 1902-
Publicado: (1953)

Peripheral Nerve Injury: Stem Cell Therapy and Peripheral Nerve Transfer
por: Sullivan, Robert, et al.
Publicado: (2016)

The Physiology of Peripheral Nerve Injury
por: Ritchie, Anthony E.
Publicado: (1945)

PERIPHERAL NERVE INJURY IN SPORTS
por: Radić, Borislav, et al.
Publicado: (2018)

G9a inhibits CREB-triggered expression of mu opioid receptor in primary sensory neurons following peripheral nerve injury
por: Liang, Lingli, et al.
Publicado: (2016)

Hedysari Extract Improves Regeneration after Peripheral Nerve Injury by Enhancing the Amplification Effect
por: Wang, Zhiyong, et al.
Publicado: (2013)

A case study in cross-talk: the histone lysine methyltransferases G9a and GLP
por: Collins, Robert, et al.
Publicado: (2010)

G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells
por: Zhang, Tuo, et al.
Publicado: (2016)

Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage
por: Ginjala, Vasudeva, et al.
Publicado: (2017)

The Whole Transcriptome Involved in Denervated Muscle Atrophy Following Peripheral Nerve Injury
por: Weng, Jian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6k2vdculciokefnco3238tm1ib