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How transcription circuits explore alternative architectures while maintaining overall circuit output

Transcription regulators bind to cis-regulatory sequences and thereby control the expression of target genes. While transcription regulators and the target genes that they regulate are often deeply conserved across species, the connections between the two change extensively over evolutionary timesca...

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Detalles Bibliográficos
Autores principales: Dalal, Chiraj K., Johnson, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588923/
https://www.ncbi.nlm.nih.gov/pubmed/28860157
http://dx.doi.org/10.1101/gad.303362.117