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Physiological/pathological ramifications of transcription factors in the unfolded protein response

Numerous environmental, physiological, and pathological insults disrupt protein-folding homeostasis in the endoplasmic reticulum (ER), referred to as ER stress. Eukaryotic cells evolved a set of intracellular signaling pathways, collectively termed the unfolded protein response (UPR), to maintain a...

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Detalles Bibliográficos
Autores principales:	Han, Jaeseok, Kaufman, Randal J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588925/ https://www.ncbi.nlm.nih.gov/pubmed/28860159 http://dx.doi.org/10.1101/gad.297374.117

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