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Abro1 maintains genome stability and limits replication stress by protecting replication fork stability

Protection of the stalled replication fork is crucial for responding to replication stress and minimizing its impact on chromosome instability, thus preventing diseases, including cancer. We found a new component, Abro1, in the protection of stalled replication fork integrity. Abro1 deficiency resul...

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Detalles Bibliográficos
Autores principales: Xu, Shengfeng, Wu, Xiao, Wu, Ling, Castillo, Andy, Liu, Jianxin, Atkinson, Erin, Paul, Atanu, Su, Dan, Schlacher, Katharina, Komatsu, Yoshihiro, You, M. James, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588928/
https://www.ncbi.nlm.nih.gov/pubmed/28860160
http://dx.doi.org/10.1101/gad.299172.117