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The physical dimensions of amyloid aggregates control their infective potential as prion particles

Transmissible amyloid particles called prions are associated with infectious prion diseases in mammals and inherited phenotypes in yeast. All amyloid aggregates can give rise to potentially infectious seeds that accelerate their growth. Why some amyloid seeds are highly infectious prion particles wh...

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Detalles Bibliográficos
Autores principales: Marchante, Ricardo, Beal, David M, Koloteva-Levine, Nadejda, Purton, Tracey J, Tuite, Mick F, Xue, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589414/
https://www.ncbi.nlm.nih.gov/pubmed/28880146
http://dx.doi.org/10.7554/eLife.27109

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