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The physical dimensions of amyloid aggregates control their infective potential as prion particles
Transmissible amyloid particles called prions are associated with infectious prion diseases in mammals and inherited phenotypes in yeast. All amyloid aggregates can give rise to potentially infectious seeds that accelerate their growth. Why some amyloid seeds are highly infectious prion particles wh...
Autores principales: | Marchante, Ricardo, Beal, David M, Koloteva-Levine, Nadejda, Purton, Tracey J, Tuite, Mick F, Xue, Wei-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589414/ https://www.ncbi.nlm.nih.gov/pubmed/28880146 http://dx.doi.org/10.7554/eLife.27109 |
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