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An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome
Many antibiotics stop bacterial growth by inhibiting different steps of protein synthesis. However, no specific inhibitors of translation termination are known. Proline-rich antimicrobial peptides, a component of the antibacterial defense system of multicellular organisms, interfere with bacterial g...
Autores principales: | Florin, Tanja, Maracci, Cristina, Graf, Michael, Karki, Prajwal, Klepacki, Dorota, Berninghausen, Otto, Beckmann, Roland, Vázquez-Laslop, Nora, Wilson, Daniel N., Rodnina, Marina V., Mankin, Alexander S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589491/ https://www.ncbi.nlm.nih.gov/pubmed/28741611 http://dx.doi.org/10.1038/nsmb.3439 |
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