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An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome

Many antibiotics stop bacterial growth by inhibiting different steps of protein synthesis. However, no specific inhibitors of translation termination are known. Proline-rich antimicrobial peptides, a component of the antibacterial defense system of multicellular organisms, interfere with bacterial g...

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Detalles Bibliográficos
Autores principales: Florin, Tanja, Maracci, Cristina, Graf, Michael, Karki, Prajwal, Klepacki, Dorota, Berninghausen, Otto, Beckmann, Roland, Vázquez-Laslop, Nora, Wilson, Daniel N., Rodnina, Marina V., Mankin, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589491/
https://www.ncbi.nlm.nih.gov/pubmed/28741611
http://dx.doi.org/10.1038/nsmb.3439

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