The pancreatic tumor microenvironment drives changes in miRNA expression that promote cytokine production and inhibit migration by the tumor associated stroma

The pancreatic adenocarcinoma (PDAC) microenvironment is largely comprised of fibrotic tumor associated stroma (TAS) that contributes to the lethal biology of PDAC. microRNA (miRNA) are small non-coding RNAs that regulate gene expression. We hypothesized that interactions between PDAC cells and TAS...

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Detalles Bibliográficos
Autores principales: Han, Song, Gonzalo, David H., Feely, Michael, Delitto, Daniel, Behrns, Kevin E., Beveridge, Mark, Zhang, DongYu, Thomas, Ryan, Trevino, Jose G., Schmittgen, Thomas D., Hughes, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589562/
https://www.ncbi.nlm.nih.gov/pubmed/28903323
http://dx.doi.org/10.18632/oncotarget.10722

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