Myeloid-derived suppressor cell and macrophage exert distinct angiogenic and immunosuppressive effects in breast cancer

The immunosuppressive tumor microenvironment is a key obstacle to hinder a cancer immunotherapy. Myeloid-derived suppressor cells (MDSCs) have been considered as a major player in immunosuppression. In this study, we find that tumor-infiltrating MDSCs (tiMDSCs) are less immunosuppressive than tumor-...

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Detalles Bibliográficos
Autores principales: Fang, Zhaoxu, Wen, Chengwen, Chen, Xiaolan, Yin, Rongping, Zhang, Chenglin, Wang, Xiaohua, Huang, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589571/
https://www.ncbi.nlm.nih.gov/pubmed/28903332
http://dx.doi.org/10.18632/oncotarget.17013

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