Base excision repair imbalance in colorectal cancer has prognostic value and modulates response to chemotherapy

Colorectal cancer (CRC) is prevalent worldwide, and treatment often involves surgery and genotoxic chemotherapy. DNA repair mechanisms, such as base excision repair (BER) and mismatch repair (MMR), may not only influence tumour characteristics and prognosis but also dictate chemotherapy response. De...

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Detalles Bibliográficos
Autores principales: Leguisamo, Natalia M., Gloria, Helena C., Kalil, Antonio N., Martins, Talita V., Azambuja, Daniel B., Meira, Lisiane B., Saffi, Jenifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589573/
https://www.ncbi.nlm.nih.gov/pubmed/28903334
http://dx.doi.org/10.18632/oncotarget.14909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589573/
https://www.ncbi.nlm.nih.gov/pubmed/28903334
http://dx.doi.org/10.18632/oncotarget.14909

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