Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to Bacillus Calmette Guérin (BCG) and to oxidative damage

The sialyl-Tn (sTn) antigen is an O-linked carbohydrate chain aberrantly expressed in bladder cancer (BC), whose biosynthesis is mainly controlled by the sialyltransferase ST6GALNAC1. Treatment with Bacillus Calmette-Guérin (BCG) is the most effective adjuvant immunotherapy for superficial BC but on...

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Detalles Bibliográficos
Autores principales: Severino, Paulo F., Silva, Mariana, Carrascal, Mylene, Malagolini, Nadia, Chiricolo, Mariella, Venturi, Giulia, Astolfi, Annalisa, Catera, Mariangela, Videira, Paula A., Dall’Olio, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589598/
https://www.ncbi.nlm.nih.gov/pubmed/28903359
http://dx.doi.org/10.18632/oncotarget.17138

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