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Toxicology and efficacy of tumor-targeting Salmonella typhimurium A1-R compared to VNP 20009 in a syngeneic mouse tumor model in immunocompetent mice

Salmonella typhimurium A1-R (S. typhimurium A1-R) attenuated by leu and arg auxotrophy has been shown to target multiple types of cancer in mouse models. In the present study, toxicologic and biodistribution studies of tumor-targeting S. typhimurium A1-R and S. typhimurium VNP20009 (VNP 20009) were...

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Detalles Bibliográficos
Autores principales:	Zhang, Yong, Cao, Wenluo, Toneri, Makoto, Zhang, Nan, Kiyuna, Tasuku, Murakami, Takashi, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Li, Shukuan, Wang, Xiaoen, Ma, Huaiyu, Singh, Arun S., Eilber, Fritz C., Hoffman, Robert M., Zhao, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589608/ https://www.ncbi.nlm.nih.gov/pubmed/28903369 http://dx.doi.org/10.18632/oncotarget.17605

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