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Association between the functional polymorphism Ile31Phe in the AURKA gene and susceptibility of hepatocellular carcinoma in chronic hepatitis B virus carriers

Aurora kinase A (AURKA) is a serine threonine kinase which affects chromosomal separation and mitotic spindle stability through interaction with the centrosome during mitosis. Two functional nonsynonymous polymorphisms of the AURKA gene (Ile31Phe and Val57Ile) have been reported recently. We analyze...

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Detalles Bibliográficos
Autores principales: Bao, Zhiyu, Lu, Lei, Liu, Xinyi, Guo, Bingqian, Zhai, Yun, Li, Yuanfeng, Wang, Yahui, Xie, Bobo, Ren, Qian, Cao, Pengbo, Han, Yuqing, Jia, Weihua, Chen, Minshan, Liang, Xinqiang, Wang, Xuan, Zeng, Yi-Xin, He, Fuchu, Zhang, Hongxing, Cui, Ying, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589629/
https://www.ncbi.nlm.nih.gov/pubmed/28903390
http://dx.doi.org/10.18632/oncotarget.18613