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Acetyl-lupeolic acid inhibits Akt signaling and induces apoptosis in chemoresistant prostate cancer cells in vitro and in vivo

The triterpenoid acetyl-lupeolic acid (ac-LA) isolated from the oleogum resin of Boswellia carterii reduced the viability of a panel of cancer cell lines more efficiently than lupeol. There was no detectable intracellular conversion of ac-LA to lupeol and vice versa. In contrast to docetaxel, ac-LA...

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Detalles Bibliográficos
Autores principales:	Schmidt, Claudia, Loos, Cornelia, Jin, Lu, Schmiech, Michael, Schmidt, Christoph Q., Gaafary, Menna El, Syrovets, Tatiana, Simmet, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589648/ https://www.ncbi.nlm.nih.gov/pubmed/28903409 http://dx.doi.org/10.18632/oncotarget.19101

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