Low body surface area predicts hepatotoxicity of nintedanib in patients with idiopathic pulmonary fibrosis

After the commercialization of nintedanib in Japan, a high incidence of hepatotoxicity resulting in treatment interruption was noted in idiopathic pulmonary fibrosis (IPF) patients treated with nintedanib in our hospital. This study aimed to clarify the risk factors for hepatotoxicity of nintedanib....

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Detalles Bibliográficos
Autores principales: Ikeda, Satoshi, Sekine, Akimasa, Baba, Tomohisa, Yamanaka, Yumie, Sadoyama, Shinko, Yamakawa, Hideaki, Oda, Tsuneyuki, Okuda, Ryo, Kitamura, Hideya, Okudela, Koji, Iwasawa, Tae, Ohashi, Kenichi, Takemura, Tamiko, Ogura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589740/
https://www.ncbi.nlm.nih.gov/pubmed/28883482
http://dx.doi.org/10.1038/s41598-017-11321-x

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