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Reovirus inhibits interferon production by sequestering IRF3 into viral factories
Upon viral infection, an arms-race between the cellular intrinsic innate immune system and viral replication is established. To win this race, viruses have established multiple strategies to inhibit the cellular response. Mammalian reovirus (MRV) constitutes a great model to study pathogenesis and l...
Autores principales: | Stanifer, Megan L., Kischnick, Christian, Rippert, Anja, Albrecht, Dorothee, Boulant, Steeve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589761/ https://www.ncbi.nlm.nih.gov/pubmed/28883463 http://dx.doi.org/10.1038/s41598-017-11469-6 |
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