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Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers

Accumulation of glycine receptors at synapses requires the interaction between the beta subunit of the receptor and the scaffold protein gephyrin. Here, we questioned whether different alpha subunits could modulate the receptors’ diffusion and propensity to cluster at spinal cord synapses. Using qua...

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Detalles Bibliográficos
Autores principales: Patrizio, A., Renner, M., Pizzarelli, R., Triller, A., Specht, C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589798/
https://www.ncbi.nlm.nih.gov/pubmed/28883437
http://dx.doi.org/10.1038/s41598-017-11264-3

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