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Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells
Replacement of lost beta cells in patients with diabetes has the potential to alleviate them of their disease, yet current protocols to make beta cells are inadequate for therapy. In vitro screens can reveal the signals necessary for endocrine maturation to improve beta cell production, however the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589819/ https://www.ncbi.nlm.nih.gov/pubmed/28883507 http://dx.doi.org/10.1038/s41598-017-11169-1 |