Cargando…
Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells
Replacement of lost beta cells in patients with diabetes has the potential to alleviate them of their disease, yet current protocols to make beta cells are inadequate for therapy. In vitro screens can reveal the signals necessary for endocrine maturation to improve beta cell production, however the...
Autores principales: | Scavuzzo, Marissa A., Yang, Diane, Borowiak, Malgorzata |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589819/ https://www.ncbi.nlm.nih.gov/pubmed/28883507 http://dx.doi.org/10.1038/s41598-017-11169-1 |
Ejemplares similares
-
Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis
por: Scavuzzo, Marissa A., et al.
Publicado: (2018) -
Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases
por: Yang, Diane, et al.
Publicado: (2016) -
Human pancreatic microenvironment promotes β-cell differentiation via non-canonical WNT5A/JNK and BMP signaling
por: Chmielowiec, Jolanta, et al.
Publicado: (2022) -
Endocrine Pancreas Development and Dysfunction Through the Lens of Single-Cell RNA-Sequencing
por: Szlachcic, Wojciech J., et al.
Publicado: (2021) -
From Mesenchymal Stromal/Stem Cells to Insulin-Producing Cells: Immunological Considerations
por: Refaie, Ayman F., et al.
Publicado: (2021)