Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function

Nonalcoholic fatty liver disease is one of the most prevalent metabolic disorders and it tightly associates with obesity, type 2 diabetes, and cardiovascular disease. Reduced mitochondrial lipid oxidation contributes to hepatic fatty acid accumulation. Here, we show that the Fas cell surface death r...

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Detalles Bibliográficos
Autores principales: Item, Flurin, Wueest, Stephan, Lemos, Vera, Stein, Sokrates, Lucchini, Fabrizio C., Denzler, Rémy, Fisser, Muriel C., Challa, Tenagne D., Pirinen, Eija, Kim, Youngsoo, Hemmi, Silvio, Gulbins, Erich, Gross, Atan, O’Reilly, Lorraine A., Stoffel, Markus, Auwerx, Johan, Konrad, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589858/
https://www.ncbi.nlm.nih.gov/pubmed/28883393
http://dx.doi.org/10.1038/s41467-017-00566-9

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