Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans

Resolvins are omega-3 fatty acid derived potent bioactive lipids that resolve inflammation and modulate transient receptor potential channels. Exogenous administration of the resolvin precursor 17-HDHA shows a strong analgesic effect in animal models of osteoarthritis and acute inflammatory pain, bu...

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Detalles Bibliográficos
Autores principales: Valdes, Ana M., Ravipati, Srinivasarao, Menni, Cristina, Abhishek, Abhishek, Metrustry, Sarah, Harris, Juliette, Nessa, Ayrun, Williams, Frances M. K., Spector, Tim D., Doherty, Michael, Chapman, Victoria, Barrett, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589894/
https://www.ncbi.nlm.nih.gov/pubmed/28883634
http://dx.doi.org/10.1038/s41598-017-09516-3

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