Early X chromosome inactivation during human preimplantation development revealed by single-cell RNA-sequencing

In female mammals, one X chromosome is transcriptionally inactivated (XCI), leading to dosage compensation between sexes, fundamental for embryo viability. A previous study using single-cell RNA-sequencing (scRNA-seq) data proposed that female human preimplantation embryos achieve dosage compensatio...

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Detalles Bibliográficos
Autores principales: Moreira de Mello, Joana C., Fernandes, Gustavo R., Vibranovski, Maria D., Pereira, Lygia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589911/
https://www.ncbi.nlm.nih.gov/pubmed/28883481
http://dx.doi.org/10.1038/s41598-017-11044-z

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