Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes

Endogenous formaldehyde is abundantly present in our bodies, at around 100 µM under normal conditions. While such high steady state levels of formaldehyde may be derived by enzymatic reactions including oxidative demethylation/deamination and myeloperoxidation, it is unclear whether endogenous forma...

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Detalles Bibliográficos
Autores principales: Nakamura, Jun, Shimomoto, Takasumi, Collins, Leonard B., Holley, Darcy W., Zhang, Zhenfa, Barbee, Jenna M., Sharma, Vyom, Tian, Xu, Kondo, Tomohiro, Uchida, Koji, Yi, Xianwen, Perkins, Diana O., Willis, Monte S., Gold, Avram, Bultman, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589919/
https://www.ncbi.nlm.nih.gov/pubmed/28883613
http://dx.doi.org/10.1038/s41598-017-11289-8

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