Visualization of ligand-induced dopamine D(2S) and D(2L) receptor internalization by TIRF microscopy

G protein-coupled receptors (GPCRs), including the dopamine receptors, represent a group of important pharmacological targets. Upon agonist binding, GPCRs frequently undergo internalization, a process that is known to attenuate functional responses upon prolonged exposure to agonists. In this study,...

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Detalles Bibliográficos
Autores principales: Tabor, Alina, Möller, Dorothee, Hübner, Harald, Kornhuber, Johannes, Gmeiner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589927/
https://www.ncbi.nlm.nih.gov/pubmed/28883522
http://dx.doi.org/10.1038/s41598-017-11436-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589927/
https://www.ncbi.nlm.nih.gov/pubmed/28883522
http://dx.doi.org/10.1038/s41598-017-11436-1

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